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Patents and Licenses

(a) Invention Disclosures filed with the University of British Columbia University-Industry Liaison Office on October 4, 1993:

(i) Oral appliance for the treatment of Snoring and Obstructive Sleep Apnea

(ii) Oral appliance for the incremental repositioning of the mandible for the treatment of Snoring and Obstructive Sleep Apnea

(iii) Oral appliance wear monitor.

(b) U.S. patent #5,409,617 issued on April 25, 1995 for a Mandibular Repositioning Appliance.

(c) U.S. Food and Drug Administration 510k market approval issued on May 25, 1995 for Klearway™ Appliance.

(d) Patent Convention Treaty publication WO95/19746 on July 27, 1995 for a Mandibular Repositioning Appliance for Snoring Prevention.

(e) Canada, United Kingdom, Spain, Japan, Australia Patent Applications filed August, 1996 for a Mandibular Repositioning Appliance for Snoring Prevention.

(f) License Agreement on May 31, 1995 between The University of British Columbia, Space Maintainers Laboratories Canada Ltd., Space Maintainers Laboratories (Vancouver) Canada Ltd. and Space Maintainers Laboratories (Ottawa) Canada Ltd. to manufacture, distribute, market and sell Klearway™ to dentists in Canada. Amended July 1, 1995 and September, 1996.

(g) License Agreement on January 26, 1995 between The University of British Columbia and Great Lakes Orthodontics Ltd. to manufacture, distribute, market and sell Klearway™ to dentists in the United States.

(h) Distributor Agreement approved on November 12, 1996 between The University of British Columbia and Great Lakes Orthodontics Ltd. to manufacture, distribute, market and sell Klearway™ to physicians and sleep laboratories in the United States.

(i) U.S. patent applied for on November 18, 1996 for a Time Monitoring Appliance with A Ivanov.

(j) Assignment Agreement filed on September 17, 1996 with University Technologies International Inc. for a Remotely-Controlled Mandibular Positioner.

(k) U.S. patent applied for on January 14, 1997 for a Remotely-Controlled Mandibular Positioner.

(l) Australian Patent #679316 issued on June 26,1997 for a Mandibular Repositioning Appliance.

(m) European Patent # EP0740538B1 issued on November 26, 1997 for a Mandibular Repositioning Appliance.

(n) U.S. patent #5774425 issued on June 30, 1998 for a Time Monitoring Appliance.

(o) U.S. patent #5826579 issued on October 27, 1998 for a Remotely-Controlled Mandibular Repositioner with J. Remmers, E. Hajduk, and R. Platt.

(p) Patent Cooperation Treaty publication CA/00853 applied for on April 15, 1999 for a Time Monitoring Appliance with A. Ivanov.

(q) Term Sheet for UBC License Agreement with Pro-Tech Services, Inc of Seattle, Washington for an oral appliance compliance monitor finalized on March 23, 2002.

(r) Patents and Patent Applications for an oral appliance compliance monitor include US Patent 5,774,425; 2,271,160, Canadian Patent Application 2,271,160; Australian Patent Application 49389/97; European Patent Application 97912003.7; Japanese Patent Application HEI.10-523026

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